Utilization of Kidneys From Deceased Donors With Primary Brain Malignancy in an Australian Setting

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Category: Brain cancer

Tags: Model 09

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Disease Area (Primary)

Brain Cancer

Disease Area (Secondary)

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First Developed

06/26/2022

Last Developed

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Software Used

R (e.g., heemod, BCEA, dampack, hesim)

Model Sponsor

Academic institution

Intervention

increase_utilization_of_kidneys

Model Validation Score

– %

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Results

Compared with current practice, decision support provided 0.3% more donors with an average transmission risk of 2%. Real-time data-linkage provided 0.6% more donors (1.1% average transmission risk) and increasing risk tolerance (accepting intermediate-risk 6.4%) provided 2.1% more donors (4.9% average transmission risk). Interventions were dominant (improved QALYs and saved costs) in 78%, 80%, and 87% of simulations, respectively. The largest benefit was from increasing risk tolerance (mean +18.6 QALYs and AU$2.2 million [US$1.6 million] cost-savings).

Conclusion

What are the key conclusions or current applications of this model?

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Utilization of Kidneys From Deceased Donors With Primary Brain Malignancy in an Australian Setting

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